Polyclonal Antibodies
Polyclonal antibodies are a mixture of antibodies produced by multiple B-cell clones that recognize several different epitopes on the same antigen. Their advantage is high affinity and the ability to amplify the signal, as multiple antibodies can bind to a single target protein. They are ideal for applications such as Western Blot (WB) or ChIP where the target protein is at a low concentration. Are you looking for a robust antibody (e.g., from Elabscience) with a high titer that is more tolerant to small changes in antigen structure? Find a validated polyclonal antibody for your target here. All products can be found here.
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Polyclonal antibodies are a mixture of molecules recognizing different epitopes on the same antigen. Their primary advantage is high sensitivity and detection robustness.
Why Choose Polyclonal Antibodies?
- Signal Amplification: Multiple antibodies binding to a single protein increase the overall signal, ideal for Western Blotting (WB).
- Tolerance to Changes: They better recognize denatured proteins or those with minor mutations or glycosylation variants.
- Applications: The preferred choice for IP (immunoprecipitation) and ChIP.
They are typically paired with conjugated secondary antibodies for final visualization.
