General Fragment Libraries
General fragment libraries form the foundation for fragment-based drug discovery (FBDD), representing an efficient alternative to high-throughput screening (HTS). These libraries contain small molecules (fragments with molecular weight typically <300 Da) with high solubility, optimized for biophysical screening methods (e.g., NMR, SPR, X-ray crystallography). Are you utilizing an FBDD approach to identify initial binding hits on your protein target and need a diversified fragment library that meets the "Rule of Three"? Find a high-solubility library designed for your biophysical screening here.
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The fundamental tool for Fragment-Based Drug Discovery (FBDD). Contains small molecules (< 300 Da) for efficient exploration of protein binding sites.
Optimization
- Fragments: Chemically linked into high-potency inhibitors.
